Tests of Generic Lamotrigine Successful
Studies published in 2015 and 2016 have established that generic versions of the anti-convulsant lamotrigine are bioequivalent to the name-brand drug (Lamictal) and to each other. Lamotrigine is used to treat epilepsy and is also prescribed for the prevention of bipolar depression.
An article by T.Y. Ting and colleagues in the journal Epilepsia in 2015 established that generic lamotrigine works similarly enough to the name brand drug that patients with epilepsy could be switched from one drug to the other without worsening seizures. More recently, M.D. Privitera and colleagues reported in the journal Lancet Neurology that different generic versions of lamotrigine were bioequivalent. No significant changes in seizure frequency or other negative outcomes were reported.
These studies show that generic versions of lamotrigine have the same anticonvulsant effectiveness as the original drug. The same should also be true for lamotrigine’s effectiveness in preventing bipolar depression.