Topiramate Plus Antipsychotic Medication Better Than Antipsychotics Alone for Schizophrenia Spectrum Disorders

May 30, 2017 · Posted in Current Treatments · Comment 

womanA 2016 meta-analysis has shown that the combination of the anticonvulsant topiramate and antipsychotic medication reduces symptoms of schizophrenia spectrum disorders more than antipsychotic medication alone. Researchers led by Christoph U. Correll analyzed the results of eight studies in which the topiramate-antipsychotic combination was compared to antipsychotics alone or with placebo.

The combination of topiramate and antipsychotic medication was superior at reducing general psychopathology, including both negative and positive symptoms of schizophrenia. The combination was also associated with lower body weight and body mass index (BMI) compared to antipsychotics alone.

The studies included in the meta-analysis used a variety of antipsychotic medications. When these were compared, the combination of topiramate and clozapine was more effective than other combinations at reducing psychopathology. However, the combination of topiramate and clozapine was also associated with less weight loss than combinations using other antipsychotics.

In terms of side effects, topiramate was associated with more paresthesia (a burning or prickling sensation, often in the hands or feet) than placebo.

The study was published in the Journal of Clinical Psychiatry.

Guanfacine Improves Cognition in Schizophrenia

April 19, 2016 · Posted in Potential Treatments · Comment 

cognitive function in schizophrenia

People with disorders on the schizophrenia spectrum often suffer cognition problems that affect skills such as the processing of information about people and social situations (social cognition) and the execution of plans (executive function). At the 2015 meeting of the Society for Biological Psychiatry, researcher Larry J. Siever reported that the drug guanfacine improved these types of thinking in people with disorders on the schizophrenic spectrum compared to placebo. Participants were enrolled in a 7.5-week training program to improve cognition.

A hysterectomy may not be your only option. Frequent painful urination, or an inability to control the flow of urine. When they do, they may include: heavy, prolonged, or irregular menstrual bleeding pain in the lower abdomen or back painful intercourse urinary problems, such as urinary frequency rectal problems, such as pain in the rectum Acircnbsp read the understanding uterine fibroids -- symptoms article why fibroids cause pain is not known. hutchins f, worthington-kirsch r, berkowitz r. Self-reported quality of urinary and defecatory function at follow-up was compared with that at baseline, and there were three possible outcomes: quality was worse, the same, or better. hutchins f, worthington-kirsch r, berkowitz r. Before you sign the consent form, understand the risks and benefits of what will be done. viagra user forum Fish oil prevents abnormal blood clotting. The pressure-applying members may be released from the cervix after a limited therapeutically effective time. viagra prices rite aid cheap viagra online with prescription Patients usually stay in the hospital overnight after uae and are given pain medication. Researchers think that more than one factor could play a role. Treatment options for uterine fibroids bynbspsally ann murphynbspnovember 4, 2009 this article will describe the treatment options available for uterine fibroids.