Lamotrigine Effective Adjunct for Lithium in Bipolar Disorder

March 7, 2012 · Posted in Peer-Reviewed Published Data 

lamotrigineIn a long-term study of bipolar patients taking lithium published in Bipolar Disorders last year, the addition of lamotrigine (or paroxetine for those who did not respond to lamotrigine) was significantly better than the addition of placebo.  Patients taking lamotrigine with lithium averaged 10 months until a recurrence of a depressive or manic episode, while patients taking placebo with lithium averaged 3.5 months until an episode.

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