Possible Heart Failure Risk with Pramipexole
February 27, 2014 · Posted in Current Treatments
We’ve written before about the drug pramipexole, which is typically used to treat Parkinson’s disease and restless legs, but can also improve depressed mood and cognition in those with bipolar disorder. The Federal Drug Administration (FDA) published a warning in 2012 that the drug may increase risk of heart failure, though more research is needed to confirm this link. In a review of existing studies, the FDA found that heart failure occurred more often in participants taking pramipexole than those taking placebo, but the finding did not reach statistical significance.