Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients

M M Bergamaschi, et al reported in Neuropsychopharmacology volume 36, pages 1219–1226 (2011) that the one of the ingredient in cannabis, the diol or cannabidiol (CBD), containing none of the usual THC which make up the vast majority of plant-based marijuana, reduces the anxiety Induced by simulated public speaking in treatment-naïve social phobia patients.  They used “CBD (600?mg) in powder, ?99.9% pure (kindly supplied by STI-Pharm, Brentwood, UK and THC-Pharm, Frankfurt, Germany),… dissolved in corn oil.”  This CBD has shown efficacy in other anxiety disorders and is FDA approved for one form of seizure disorder.  This pure form of CBD is very expensive and usual preparations of available cannabis contain mostly THC and only minute amounts of CBD.  Thus, the generalizability of these results to people using the widely available preparations of cannabis is extremely unlikely. 

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