The Addition of Fish Oil to Cognitive Behavioral Case Management is Not Effective for Youth Depression

In a relatively large placebo-controlled study adding a combination of 840 mg of eicosapentaenoic acid (EPA) and 560 mg of docosahexaenoic acid (DHA) versus placebo did not help treat depressed youth undergoing cognitive behavioral case management (CBCM) (Amminger et al, Biol. Psychiatry, June 22, 2023).

These findings add to the ongoing inconsistency of the effectiveness of Omega 3 Fatty Acids in treating depression. It had appeared more effective in younger than older depressed patients, but now even this trend appears unreliable.

A meta analysis does support use Omega 3 Fatty Acids for ADHD, however.


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